Allergen Responses

 

Allergy is described as an exaggerated reaction of the immune system to foreign bodies and substances that are not harmful to normal non-allergic individuals. The response by the immune system is exaggerated since it treats these foreign bodies as threats to the health of the body, instead of discarding and eliminating them like it normally would. This reaction is workable if a certain response of the immune system is activated.

The mechanism of allergies begins with the so-called exaggerated reaction of the immunity process to antigens. Antigens are specific substances that trigger the immunity process to release its antibodies. Once an antigen invades the body, the immune system will try to work out the nature of antigen by identifying whether it is dangerous or not. In people who have not developed allergies, all antigens are not harmful.

Still, for people who had antigens which underwent previous sensitization, selected antigens are treated by the body as threats. Among allergic people, the invasion of an antigen will trigger a series of immune response referred to as allergic cascade. The result of that are allergic attacks and symptoms characterizing the specific allergy or the specific body part affected by the antigen.

The antigen to which an individual is allergic to is known as allergen which comes in sorts of animal dander, foods, drugs, chemicals, pollens, dust mites and others.

Allergens can penetrate the body through various entry points. These entry points are essentially distinguished by the nature of the allergen. For example, nasal passages are the passageways for pollens, dust mites, dust, molds and different minute objects.

Allergens can likewise affect the body, but do not necessarily have to penetrate the inner body, through the contact with the skin or mucous tissue layers. Topical chemical substances and substances are frequently the culprits of allergic responses on the skin. This hypersensitivity differs with other allergic responses as it only triggers cells of inflammation which are found on the superficial layers of the skin and not the specific antibody that reacts to allergens- the IgE.

Although, for some substances, contact does not end with the skin, they often times seep through the underlying structures to cause more severe allergic responses. There are also allergens that are injected to the body. These typically comprises materials that are injected mechanically or chemicals that insects carry. Lastly are the allergens that are ingested which compose of a mixture of food that typically trigger allergic responses among humans, treatments and drugs. In over sensitive individuals, even water components may pose as allergens.

The allergic cascade happens in three phases. It starts with the encroachment in a common substance of the body’s system. If the immune system detects it as harmless, it won’t respond aggressively, resulting in the antigen’s elimination. However, if the immune system detects it as a threat, it will make IgE or immunoglobulin E, an antibody that reacts to allergens, in massive quantities. IgE in turn will plot the allergen as harmful and will develop immune side effects in succeeding encounters.

After sensitization comes another encounter with the antigen. By this moment, your system has already developed exaggerated responses. Attributable to the release off some chemicals into the bloodstream as it tries to eradicate the antigen, the body will go through the symptoms of the allergy.

These symptoms are the natural consequences of the immune response.

 

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